AIDS Treatment News

U.S. Conference on AIDS will go forward in Houston; new scholarships, September 16 deadlines

The National Minority AIDS Council has announced an extended registration deadline--September 16--for the United States Conference on AIDS (USCA) to be held in Houston. Texas, from September 27-October 2. NMAC thought carefully about postponing or canceling the conference, Nit decided that "those impacted by Hurricane Katrina need you more than ever. This is your opportunity to strengthen USCA's response in Houston, where so many people impacted by this tragedy have been relocated." N...[ Details... ]

Medicare HIV fact sheet: caution re January 2006

A two-page fact sheet on Medicare and HIV is available from the Kaiser Family Foundation, http://www.kff.org/hivaids/7171-02.cfm Persons on Medicare (not to be confused with Medicaid) will need to make important decisions for the new prescription-drug coverage (Medicare Part D) that begins in January 2006. This fact sheet can help them get ready. How many HIV patients will be affected? According to the best information available, cited by the fact sheet, 19% of persons in HIV care were ...[ Details... ]

PA-457, new kind of antiretroviral: ten-day clinical trial results

On August 22 Panacos, a pharmaceutical company. released results of a small, 10-day human trial of the maturation inhibitor PA-457, the first time more than a single dose of this compound has been tested in HIV-positive people. The largest of the four doses tested reduced viral load by a median of one log (ten fold) for the six patients in that group. No dose-limiting toxicity was found. PA-457 is important because it works by a new mechanism of action, different from any approved drug: therefo...[ Details... ]

No July 2005 AIDS Treatment News

AIDS Treatment News did not publish an issue in July. All individual subscriptions are managed issue number, not calendar year, and will automatically be extended to include the correct number of issues.COPYRIGHT 2005 John S. JamesCOPYRIGHT 2005 Gale Group...[ Details... ]

Hurricane Katrina HIV-related information

September 14: Besides the thousands who have been killed, about a million people have had to leave their homes, and most cannot go back soon--if ever. Hundreds of thousands have lost their jobs and income, and many have lost papers and medicines, or are in other states where their health coverage might not apply. An estimated 8,000 of those who had to evacuate have HIV. Here are some Web and telephone starting points for finding HIV-relevant information, especially but not only on medical care: we also...[ Details... ]

Communication in a disaster: success of text messages

Police and other communication failed in New Orleans, and city officials could not reach each other. But text messages did get through. While police and city offices could not communicate at all, people in the disaster area could update their blogs by email and report to the world, using their Blackberry or other wireless email machine, often recharged by car battery since no other power was available. Reporters discovered that they could file stories from New Orleans by text messages, when they had no...[ Details... ]

HIV protease inhibitors vs. malaria

Researchers at San Francisco General Hospital and the Howard Hughes Institute tested seven HIV protease inhibitors in the laboratory and found that all of them have activity against Plasmodium falciparum at concentrations found in patients. The best one in their tests was Kaletra. "These findings suggest that use of HIV-1 protease inhibitors may offer clinically relevant antimalarial activity." Comment: If protease inhibitors that were never designed or optimized for malaria can be ac...[ Details... ]

Hepatitis C and unsafe sex: there is some risk

By far the biggest risk of getting hepatitis C is from injecting drugs with shared needles. It has long been known that sexual transmission is much less common, but it can occur. Now some more data are available from the Swiss HIV Cohort Study. This study recently reported that among participants with a history of injection drug use, there were 7.4 new cases of hepatitis C per 100 patient year--compared to 0.23 per 100 patient years for those without the drug use. Among those who did not inject...[ Details... ]

Major medical journals will require that randomized trials be registered

Anyone conducting medical research on humans is already required to register most major trials in public databases, under international standards and the laws of many countries. But this requirement has often been ignored or evaded by companies that do not want to let competitors know what they are doing. In May 2005 the New England Journal of Medicine, JAMA (Journal of the American Medical Association), The Lancet, Annals of Internal Medicine, and other journals, have announced that for trials that st...[ Details... ]

Journal will require clinical trials to summarize earlier results

Starting in August 2005, The Lancet "will require authors of clinical trials submitted to The Lancet to include a clear summary of previous research findings, and to explain how their trial's findings affect this summary." In a statement published July 9, The Lancet explained that much of the reason for this requirement is to prevent research on patients that is unethical because it does not need to be done at all, as the superiority of one treatment tested over another was already kn...[ Details... ]


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