In the first experiment of its kind, investigators at the Center for Cancer Nanotechnology Excellence Focused on Therapy Response (CCNE-TR), based at Stanford University, have shown that single-walled carbon nanotubes (SWCNTs) wrapped in poly(ethylene glycol), or PEG, can successfully target tumors in living animals. The results of this work, which was conducted by Hongjie Dai, Ph.D., and coll...Monday, 8-Jan-2007 / [ Details... ]
An MIT engineer and Italian colleagues will report the invention-which may one day replace the ubiquitous Petri dish for growing cells-in PLoS ONE.Shuguang Zhang, associate director of MIT's Center for Biomedical Engineering, is a pioneer in coaxing tiny fragments of amino acids called self-assembling peptides to organize themselves into useful structures. Working with visiting graduate student Fab...Tuesday, 2-Jan-2007 / [ Details... ]
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), and colleagues at the University of Virginia in Charlottesville have succeeded in imaging, in unprecedented detail, the virus that causes influenza.A team of researchers led by NIAMS, Alasdair Steven, Ph.D., working with a version of the seasonal H3N2 strain of influenza A virus, has been able to distinguish five different kinds of influenza virus ...Tuesday, 2-Jan-2007 / [ Details... ]
A new analysis of the Federal government's efforts to study the environmental, health, and safety (EHS) implications of nanotechnology concludes that sound management will play as important a role as good science when it comes to addressing these concerns. This analysis, conducted by ICF International, based in Fairfax, VA, highlights the urgent need to develop an integrated research framework that will fund not only good science, but science designed to support sound risk management decisions. ...Monday, 18-Dec-2006 / [ Details... ]
In an attempt to determine what factors make one nanoparticle better than another at targeting tumors, a team of investigators in Korea have conducted a systematic tumor-targeting study of a variety of self-assembling nanoparticles. The results of these experiments identified several factors that appear to play a major role in determining a given particle's tumor-targeting characteristics.Reporting its work in the journal Biomaterials, a research team headed by Sang Yoon Kim, Ph.D., of th...Monday, 18-Dec-2006 / [ Details... ]
Using a polymer coating designed to resemble the outer surface of a cell membrane, a team of investigators led by Steve Armes, Ph.D., of the University of Sheffield in the United Kingdom, has created a highly stable, biocompatible magnetic nanoparticle expected to improve the sensitivity of magnetic resonance imaging (MRI). This work is reported in the journal Langmuir.The investigators first created the polymer by joining two polymers that each have constituents found on the surface of c...Monday, 18-Dec-2006 / [ Details... ]
Quantum dots, used increasingly as bright fluorescent markers in basic research and diagnostic assays, must be coated, or capped, with one of a wide variety of organic molecules in order to stabilize these nanocrystals and prevent them from aggregating when added to water. Once coated, researchers then add a targeting agent, such as an antibody or aptamer, that enables the quantum dot to bind tightly to a biomolecule of interest. Michael Strano, Ph.D., and colleagues at the University of ...Monday, 18-Dec-2006 / [ Details... ]
Though gene therapies hold great promise for treating cancer, it has proven difficult to deliver therapeutic genes efficiently into cancer cells. Animal studies have shown that polymeric and lipid-based nanoparticles have the potential to overcome this delivery obstacle, and at least one nanoparticle-based gene therapy is in human clinical trials. Now, thanks to research conducted at Carnegie-Mellon University and the University of Pittsburgh, gene therapy researchers have yet another nanoscale ...Monday, 18-Dec-2006 / [ Details... ]
In the first experiments of their kind, researchers have determined that carbon nanotubes injected directly into the bloodstream of research lab animals cause no immediate adverse health effects and circulate for more than one hour before they are removed by the liver. These findings are from the first in vivo animal study of polymer-coated carbon nanotubes, a nanomaterial that researchers hope will prove useful in diagnosing and treating disease."We sampled tissues from a dozen organs, a...Monday, 18-Dec-2006 / [ Details... ]
Nanoscale, inorganic fluorescent imaging agents such as quantum dots have become an important tool for researchers studying key biomolecules involved in cancer. At the same time, magnetic iron oxide nanoparticles are proving to be useful in detecting tumors and metastatic lesions thanks to their ability to act as powerful contrast agents for use with magnetic resonance imaging (MRI). Now, researchers at Korea's Yonsei University, have married the best characteristics of these two types of nanopa...Monday, 18-Dec-2006 / [ Details... ]
...Prev 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 Next...
Total: 958