Treatment of dyspepsia with antacids and lidocaine - Tips from Other Journals

Date: Dec, 1990

Treatment of dyspepsia in the acute setting often involves oral administration of an antacid in combination with viscous lidocaine. Welling and Watson conducted a randomized, patient-blinded study to evaluate the efficacy of an antacid-viscous lidocaine preparation in the treatment of dyspepsia.

Patients presenting with dyspeptic symptoms were randomized to receive 30 mL of antacid or 30 mL of antacid mixed with 15 mL of 2 percent viscous lidocaine (GI cocktail). Thirty-four patients received antacid, and 39 received the GI cocktail.

Patients were asked to rate their pain on a linear analog pain scale prior to and 30 minutes after treatment. Both groups reported similar levels of pain at baseline. However, the group that received antacid plus lidocaine reported significantly greater pain relief after treatment than the group that received only antacid. No adverse effects were noted with either treatment.

The study results suggest that the combination of viscous lidocaine and an antacid provides a significantly greater degree of immediate pain relief than antacid alone in patients with dyspepsia. (Annals of Emergency Medicine, July 1990, vol. 19, p. 785.)

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